Recording issues as I find them. This is on a Snow Leopard clean install, 24 inch iMac (2.33 Core 2 Duo, 2GB RAM).

• As mentioned previously, system wide folder settings are not getting applied.
• iCal never finishes restoring from iCal exported calendar backup, stuck half-way through.
• The automatic spell checker in Safari textareas mark many correctly spelled words as misspelled, usually at the beginning of the sentences (such as the one I’m typing in right now). Often, the spell checker ‘forgets’ commonly misspelled words in its suggestions (such as not suggesting “receive” when typing “recieve”).
• Arabesque screensaver is noticeably a bit laggy and jumpy (it was perfectly smooth under Leopard). [CoreAnimation changes making high-end graphics programming go haywire?]
• Full-screen Hulu videos are noticeably jumpy, even though full-screen SWFs and full-screen HD YouTube videos appear to be fine.
• Both in QuickTime X and QuickTime 7 are now slightly jumpy when playing very high definition video in windowed mode (works fine in full-screen mode). Tested with my copy of the Speed Racer Trailer (1918 by 1078 pixels).
• Transitions between windowed and full-screen modes of QuickTime are jumpy. [CoreAnimation again?]